ea0063gp225 | Adrenal and Neuroendocrine - Clinical (1) | ECE2019
Cho Du-Hyong
, Park Jung-Hyun
, Lee Jee Young
, Lee Hyeon-Ju
, Jo Inho
Previously, we reported that aphidicolin acutely increases nitric oxide (NO) production in bovine aortic endothelial cells (BAECs) by increasing phosphorylation of endothelial nitric oxide synthase at serine 1179 (p-eNOS-Ser1179) and decreasing phosphorylation at serine 116 (p-eNOS-Ser116) without altering eNOS protein expression. Here, we demonstrate that prolonged treatment with aphidicolin (over 24 h) also increased NO production in BAECs. Unlike the a...